Accelerate Biological Research
info@kendallscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-617.299.7367 (Int’l)
+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-617.299.7367 (Int’l)
For quotations, please use our online quotation form, and you may also contact us by
service@kendallscientific.com
+1-888.733.6849 (Toll-free)
+1-617.299.7367 (Int’l))
+1-888.733.6849
Our customer service representatives are available 24 hours, Monday through Friday to assist you.| Reactivity | Human Mouse Rat |
| Tested applications | IHC IF |
| Recommended Dilution | IHC 1:50 - 1:100 IF 1:100 - 1:200 |
| Observed MW | Refer to Figures |
| Immunogen | A phospho specific peptide corresponding to residues surrounding T423/402/421 of human PAK1/2/3 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | p21-activated kinase 1; PAK-1; p65-PAK; Alpha-PAK; |
The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
N/A
Copyrights © 2014 Kendall Scientific, 250 Parkway Drive, Suite 150 Lincolnshire, IL 60069
